Study on preparation of Chitosan nanoparticle as protein delivery carrier for drug delivery application
Abstract
This work investigates the polyanion initiated gelation process in fabricating chitosan (CS)-tripolyphosphate (TPP) nanoparticle intended to be used as protein delivery carrier. Variations in cross-linking agents, CS/TPP weight ratio and solution pH were investigated. The chitosan nanoparticles were characterized by several analytical techniques such as FT-IR, XRD, FE_SEM and TEM. Finally, protein loading efficiency (LE) and protein loading capacity (LC) were investigated.
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đánh giá
Published
2012-10-03
Issue
Section
ARTILES
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