Studying antioxidant, antibacterial and antifungal activities of Eleutherine bulbosa bulbs

Tóm tắt

In this investigation, the total polyphenol content (TPC) and total flavonoid content (TFC) of E. bulbosa bulbs were quantified using the Folin–Ciocalteu and aluminum chloride methods, respectively. The antioxidant capacity was evaluated using DPPH and ABTS radical scavenging assays. Additionally, the antibacterial and antifungal activities of fractionated extracts from E. bulbosa bulbs were assessed. Results showed that the TPC and TFC in the crude ethanol extracts of E. bulbosa bulbs were 93.51 ± 0.60 mg GAE/g and 32.25 ± 0.25 mg QE/g extract, respectively. The antioxidant activity of the ethyl acetate extract from E. bulbosa bulbs exhibited significant potency, with IC₅₀ values of 103.49 µg/mL and 141.25 µg/mL for the DPPH and ABTS assays, respectively. The ethyl acetate extract demonstrated the highest antibacterial activity against A. hydrophila, with the largest zone of inhibition measuring 26.51 ± 0.15 mm. It also indicated a potent antifungal effect of E. bulbosa bulb extracts, with 96.8% inhibition against B. dothidea at 312.5 µg/mL and a MIC value of 10,000 µg/mL. Therefore, the development of innovative food and pharmaceutical products derived from the bulbs of E. bulbosa is of considerable interest.