VIETNAMESE Phellinus baumii FRUITING BODY, A POTENTIAL SOURCE OF ANTIOXIDANT AND α-AMYLASE INHIBITORY AGENTS

DOI: 10.18173/2354-1059.2021-0054

  • Mai Phuong Thuy
  • Do Thi Hong
  • Le Thi Tuyet Mai
  • Le Thi Phuong Hoa
Từ khóa: Phellinus baumii, phenolics, DPPH scavenging activity, reducing power, α-amylase inhibition.

Tóm tắt

n-Hexane, ethyl acetate, and butanol fractions from methanol extract of Vietnamese Phellinus baumii fruiting body consisted of phenolics, flavonoids, and terpenoids. Ethyl acetate and butanol fractions showed a high level of total phenolics. Ethyl acetate fractions possessed the highest phenolic content (532.96 ± 19.95 mg GAE\g), accounting for approximately 53% fraction dry weight. Free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging capacity of all fractions correlated with their total phenolic content. Ethyl acetate fraction exhibited the strongest capacity with an IC50 value of 0.059 mg\mL, equivalent to nearly 50% of ascorbic acid’s capacity. Its ferric reducing power was off more than half of quercetin and acid ascorbic at the concentration of 0.2 mg\mL. Ethyl acetate also had remarkable α-amylase inhibitory activity (IC50= 0.38 mg\mL). The results suggested P. baumii fruiting body as a potent source for antioxidative and α-amylase inhibitory compounds. 

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Phát hành ngày
2022-02-21
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