Chemical constituents of the bark of Sandoricum koetjape

Abstract

Sandoricum koetjape (Meliaceae) has been used in traditional medicine for the treatment of diarrhea, dysentery, and as a tonic for women after giving birth. We have studied the chemical constituents of an ethyl acetate extract of the bark of the species collected in Binh Duong Province and isolated five compounds, bryononic acid, 3-oxo-olean-12-en-30-oic acid, koetjapic acid, 4-methylbenzoic acid and 4-methylbenzoate ethyl. Structure elucidation was performed using mainly 1-D and 2-D NMR techniques.