Synthesis of novel ursolic acid derivatives
Abstract
ABSTRACT
Some novel Ursolic Acid (UA) derivatives were designed and synthesized with substitution at positions of C-3-OH and C-28-COOH of UA, the product (1)-(6) has the yeild higher than (7)-(9), in reaction UA with CDI (10) has medium yield. These compounds showed ability ester reaction to product was easily, form these products give pharmacological activity better than UA .Their structures were confirmed using 1H-NMR.
điểm /
đánh giá
Published
2012-12-06
Issue
Section
ARTILES
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