Synthesis and investigating the detoxification ablity of KBDO against yperite

Abstract

Potassium 2.3-butanedione monoxime (KBDO) salt is one of the highly effective decontaminations for neurotoxins and blister agents; hence, it is the main ingredient in the RSDL Decontamination Kit. This paper presents the synthesizing KBDO from 2.3-butanedione monoxime (DAM) and KOH or t-BuOK under different reaction conditions and decontamination surveys of product with the yperite. The composition and structure of the products were confirmed by IR, NMR, EDX spectroscopy methods. Furthermore, the detoxification mechanism of KBDO with HD was proposed by determining the intermediate product of the reaction by NMR spectroscopy.