QUALITATIVE AND QUANTITATIVE ANALYSIS OF FLAVONOIDS IN ARTOCARPUS TONKINENSIS LEAVES BY HIGH PERFORMANCE LIQUID CHROMATOGRAPHY - MASS SPECTROMETRY (HPLC-MS)

  • Nguyễn Thị Thùy Linh
  • Bá Thị Châm
  • Nguyễn Thị Hoàng Anh
  • Trần Đức Quân
  • Đào Đức Thiện
  • Nguyễn Thanh Tâm
  • Bùi Kim Anh
  • Đỗ Quốc Việt
  • Lê Thị Hồng Nhung
  • Domenico V. Delfino
  • Trịnh Thị Thủy
Keywords: Artocarpus tonkinensis, flavonoids, maesopsin 4-O--Dglucopyranoside, HPLC-MS

Abstract

HPLC-ESI-MS method was used for the identification of the flavonoids and
quantitative determination of the flavonoid constituents in the water extract of
Artocarpus tonkinensis leaves. Seven flavonoids were unambiguously identified
as catechin (1), alphitonin 4-O--D-glucopyranoside (2), maesopsin 4-O--Dglucopyranoside (3), quercetin 3-O--D-glucopyranoside (4), kaempferol-3-O-
-D-glucoside (5), quercetin (6) and kaempferol (7), by comparing their
retention times, UV and ESI-MS spectra with those of the authentic isolated
compounds. Additionally, the main compounds were 2 and 3, with hight yield
(2.86 and 2.45 mg/g, respectively) in this plant leaves.

điểm /   đánh giá
Published
2020-11-16
Section
RESEARCH AND DEVELOPMENT