EXTRACTION OF TAMANU OIL FROM Calophyllum inophyllum L. SEEDS BY ULTRASOUND-ASSISTED METHOD AND TESTING WOUND CARE TREATMENT

  • Nguyen Huu Hieu
  • Lu Thi Mong Thy
  • Truong Le Khoi
  • Tran Do Dat
  • Phan Le Thao My
  • Vuong Hoai Thanh
  • Nguyen Duc Viet
  • Huynh Khanh Duy
  • Hoang Minh Nam
  • Mai Thanh Phong
Từ khóa: Tamanu, ultrasound, response surface methodology, Box-Hunter, wound healing

Tóm tắt

Tamanu oil was extracted from Calophyllum inophyllum Linn. by ultrasound-assisted method. Four solvents including n-hexane, ethanol, petroleum ether, and ethyl acetate were investigated. Response surface methodology was employed to investigate effects of time, temperature, and solvent-to-material ratio on the extraction yield. Tamanu oil extraction yield was achieved of 55.15% under conditions including time of 23 minutes, temperature of 42 °C, solvent-to-material ratio of 26 to 1 (v/w) mL/g. In addition, better physicochemical indices and similar fatty acid components compared to that of commercial oil were reported indicating the quality of the extracted oil. Wound healing abilities of the extracted tamanu oil was also tested on Swiss albino mice and a commercial product showing the potential agent for wound care treatment of tamanu oil based on the recorded better wound healing ability.
Keywords: Tamanu, ultrasound, response surface methodology, Box-Hunter, wound healing

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2020-11-26
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