FABRICATION AND CHARACTERIZATION OF CELLULOSE DERIVATIVES-BASED HYDROGEL

  • Le Thi Kim Anh
  • Truong Thi Phuong Dung
  • Huynh Nguyen Anh Tuan
  • Giang Ngoc Ha
Từ khóa: Celluloses, hydrogel, polymer, gel time, gel fraction, water uptake

Tóm tắt

Hydrogel materials have been extensively studied by many research groups owing to their wide application. The green approach in hydrogel fabrication might include polymers from natural sources. Cellulose derivative is a potential candidate because of its biocompatibility and readily availability. In this study, hydroxypropyl methyl cellulose (HPMC), hydroxypropyl cellulose (HPC), hydroxyethyl cellulose (HEC) and sodium carboxymethyl cellulose (CMC or NaCMC) shall be crosslinked with glutaraldehyde to confirm the ability to fabricate the cellulose-based hydrogel. The investigation showed that HPMC was not suitable for hydrogel fabrication due to low gel-time signal and small gel fraction (~10%). The gel time signal could be detected with only CMC solution. Accordingly, the CMC sample had the highest gel fraction (89%). CMC and HEC were comparable in water uptake (80 to 120%). HPC solution could be gelled at a higher concentration of glutaraldehyde and a completely gelled state of 100% gel fraction could be achieved. However, significantly large water uptake (up to 2000%) was detected with HPC - based samples.

điểm /   đánh giá
Phát hành ngày
2022-10-19
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