A study of pathological characteristics of pediatric non-hodgkin lymphoma based on 2008 version of the world health organization classification of lymphoid neoplasms at Children’s Hospital 1

Abstract

     

Introduction:

Objective: To evaluate the characteristics of children with non-Hodgkin lymphomas at Children’s Hospital 1. Methods and Materials: Descriptive study the pathological characteristics of 107 cases of pediatric non- Hodgkin lymphoma diagnosed at Children’s Hospital 1 from 2013 to 2017 based on the 2008 WHO

     

Results: Pediatric non-Hodgkin lymphoma induced children from new born to 15 years old, most commonly children over 5 years old (60.7%). Male is predominant than female; male- female ratio is

lymphomas are aggressive. The most common type was diffuse large B cell lymphoma 29%, following lymphoblastic lymphoma 18.7%, anaplastic large cell lymphoma 17.8%. Peripheral lymph nodes were involved 52.3%, following the gastrointestinal tracts (GI) 11.2%, skin-soft tissues were involved 8.4%, bone 7.5%, mediastinum 7.5%, genital tracts 6.5%, pharyngeal tissues 6,5%. Non-Hodgkin lymphomas of GI tracts were Diffuse Large B cell lymphoma (50%) and Burkitt lymphoma (41.7%).