DETERMINATION OF NICOTIN IN HUMAN URINE BY USING SOLID-LIQUID EXTRACTION AND GC/MS. PART 2. DETERMINATION OF NICOTINE AND ITS METABOLITES

  • Trần Thị Thanh Vân
  • Thành Thị Thu Thủy

Abstract

The aim of our research is to determine the content of nicotine in human urine by using solid–liquid extraction technique and gas chromatography- mass pectrometry (GC-MS). In part 1, the procedures of isolation of nicotine from urine by solid–liquid extraction and determination of nicotine by GC-MS were reported. In part 2, the results in determination of nicotine and its metabolite in urine samples taken from 20 non-smoking and 10 smoking volunteers will be reported. As a result, the content of nicotine in urine ranged from 0.042 mg/l to 2.074 mg/l. It is worthy to note that four in ten non-smoking person showed nicotine content higher than

Vietnam’s standard.

điểm /   đánh giá
Published
2016-01-12
Section
Articles