Current nanocarriers in therapeutic improvement of Andrographolide

  • Van Hong Nguyen*, An Hong Nguyen Pham
Từ khóa: A. paniculata, Andrographolide, herbal, nanocarriers, therapeutic effect

Tóm tắt

Currently, herbs have been investigated for novel bioactivities and improvement of traditional therapeutic effectiveness. Among them, Andrographis paniculata, with the active component Andrographolide, is well recognized as an antiinflammatory, anti-bacterial, anti-cancer, anti-hypertensive, anti-hyperglycaemic, hepatoprotective, and antihyperlipidaemic compound. However, Andrographolide has poor physicochemical properties that limit its medical application. In this review article, nano drug delivery systems including nanovesicles, inorganic nanoparticles, lipidbased nanoparticles, polymeric nanoparticles, nanocrystals, nanoemulsions, and microemulsions, which can deliver Andrographolide through different routes such as oral, injection, or dermal, and their influences in increasing treatment benefits are presented.


Van Hong Nguyen*, An Hong Nguyen Pham

Pharmaceutical Engineering Lab, School of Biomedical Engineering, International University,
Vietnam National University, Ho Chi Minh city

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