Development of direct C-3 difluoromethylation reaction for application in synthesis of quinoline-related drugs
Từ khóa:
C-H activation, difluoromethylation, drug synthesis, quinoline
Tóm tắt
Fluorine holds a prominent position within the realm of drug discovery and development, substantiated by its presence in approximately 25% of drugs approved by the US Food and Drug Administration (FDA). Consequently, the advancement of new fluorination reactions stands as a pivotal area in medicinal chemistry...
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đánh giá
Phát hành ngày
2024-03-15
Chuyên mục
PHYSICAL SCIENCES