Anti-inflammatory effect of gallic acid-conjugated chitooligosaccharides in lipopolysaccharide-stimulated RAW 264.7 macrophages

  • Van-Hoai Bui, Hong-Tham N. Vo, Thanh-Tuan Duong, Dai-Nghiep Ngo*
  • Van-Hoai Bui, Hong-Tham N. Vo
  • Se-Kwon Kim
Từ khóa: anti-inflammatory activity, chitooligosaccharide, chitooligosaccharide conjugated gallic acid, nitric oxide, RAW 264.7 macrophage cells

Tóm tắt

The aim of the present study is to investigate the anti-inflammatory effect of gallic acid grafted onto COS chains (GA-COS), focusing on the reduction of nitric oxide production, downregulation of inflammatory signals such as inducible nitric oxide synthase (iNOS), gene expression of cytokines such as TNF-α, IL-1β, IL-6, and nuclear factor kappa B (NF-κB) signalling, including the p50 and p65 subunits...

Tác giả

Van-Hoai Bui, Hong-Tham N. Vo, Thanh-Tuan Duong, Dai-Nghiep Ngo*
Deparment of Biochemistry, Faculty of Biology-Biotechnology, University of Science, Vietnam National University - Ho Chi Minh City, 227 Nguyen Van Cu Street, Ward 4, District 5, Ho Chi Minh City, Vietnam   Vietnam National University - Ho Chi Minh City, Linh Trung Ward, Thu Duc City, Ho Chi Minh City, Vietnam
Van-Hoai Bui, Hong-Tham N. Vo
Ho Chi Minh City University of Industry and Trade (HUIT), 40 Le Trong Tan Street, Tay Thanh Ward, Tan Phu District, Ho Chi Minh City, Vietnam
Se-Kwon Kim
Department of Marine Science and Convergence Engineering, College of Science and Technology, Hanyang University, 55 Hanyangdaehak-ro, Sangnok-gu, Ansan-si, Gyeonggi-do 11558, Korea
điểm /   đánh giá
Phát hành ngày
2024-03-15
In ra
Số. 1C (2024): MARCH 2024 . VOLUME 66 NUMBER 1
Chuyên mục
LIFE SCIENCES