Inducement of apoptosis in HepG2 cells by total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay

  • Hoang Nghia Son
  • Nguyen Trung Quynh Nhu
  • Diep Trung Cang
  • Nguyen Le Huy Thinh
  • Dang Dang Khoa
  • Truong Xuan Dai
  • Nguyen Thi Phuong Thao
  • Le Thanh Long

Tóm tắt

This study aimed to evaluate the effect of total extract of Scutellaria barbata and Pseuderanthemum bracteatum Imlay on HepG2 cell line. The results showed that total extract reduced HepG2 cell density for 48 hours of treatment. The total extract induced the changes expression of apoptosis-related genes in HepG2 cells including Bcl-2 and caspase family. Moreover, the ratio of apoptotic cells was associated with an increase of total extract concentration.

điểm /   đánh giá
Phát hành ngày
2019-06-11
In ra
Tập. 16 Số. 3 (2019): Khoa học Tự nhiên và Công nghệ
Chuyên mục
Bài viết A