EVALUATION OF ANTIBACTERIAL AND ANTIOXIDANT ACTIVITY OF EXCOECARIA COCHINCHINENSIS L. IN TUYEN QUANG PROVINCE

Abstract

This study evaluated the antibacterial and antioxidant activities of the crude extract (EC); fractional extracts: n-hexane (ECH), ethyl acetate (ECE) and methanol (ECM) from the leaves of Excoecaria cochinchinensis in Tuyen Quang. The following results: Crude extract (EC) inhibited the growth of 4 strains of bacteria and fungi Bacillus subtillis, Staphylococcus aureus, Fusarium oxysporum and Saccharomyces cerevisiae; n-hexane (ECH) inhibited the growth of 3 strains of Bacillus subtillis, Staphylococcus aureus and Saccharomyces cerevisiae; High ethyl acetate (ECE) exhibited activity against strains of Bacillus subtillis, Staphylococcus aureus, Fusarium oxysporum and Saccharomyces cerevisiae; and high methanol (ECM) of red monocarpus plants resistant to Escherichia coli and Bacillus subtillis strains were all with MIC values ​​of 200 mg/ml. Crude extract (EC) represents the ability to neutralize free radicals SC 65.44 ± 1.2%, corresponding to SC₅₀ value of 50.32 µg/mL. In the high-fraction extracts ECE exhibited the best antioxidant activity with DPPH assay with free radical neutralization ability SC 72.18 ± 1.1%, corresponding to SC₅₀ value of 50.32 µg/mL. This research has contributed to supplement and improve the medicinal value of this precious medicinal plant.