Surgical Outcomes of Burr-Hole Drainage for Chronic Subdural Hematoma: A Case Series at Ha Tinh Provincial General Hospital
Objective: To evaluate the surgical outcomes of chronic subdural hematoma (CSDH) treated at Ha Tinh Provincial General Hospital. Methods: A descriptive case series study with retrospective and prospective data collection was conducted on 74 patients with CSDH who underwent surgical treatment at Ha Tinh Provincial General Hospital between January 2023 and January 2026. Results: The mean age was 69.22 ± 13.81 years, and 83.8% of patients were male. All patients underwent single burr-hole craniostomy under local anesthesia with premedication. Hematomas were predominantly located on the left side (47.3%) and were hypodense on computed tomography in 73.0% of cases. The mean midline shift was 8.14 ± 4.79 mm. Postoperatively, 83.8% of patients showed improvement in motor function. Most patients (75.3%) experienced no postoperative complications. The most common complications were postoperative bleeding (7.8%) and pneumonia or urinary tract infection (9.1%). The Karnofsky Performance Scale score improved significantly from 60.41 ± 10.98 at 1 month postoperatively to 81.78 ± 15.21 at 3 months follow-up (p < 0.05). Conclusion: Burr-hole craniostomy with irrigation and closed-system drainage appears to be a safe and effective treatment option for CSDH, with acceptable complication rates and favorable functional outcomes.
Treatment outcomes of knee osteoarthritis using electroacupuncture combined with short-wave therapy at Hai Phong Traditional Medicine Hospital, 2025-2026
Objectives: 1. To describe the clinical and X – ray characteristics of patients with knee osteoarthritis treated at the Department of Physical Therapy and Rehabilitation, Hai Phong Traditional Medicine Hospital, during 2025–2026. 2. To evaluate the treatment outcomes of electroacupuncture combined with short-wave therapy in these patients. Subjects: A total of 30 patients diagnosed with knee osteoarthritis based on clinical examination and radiographic findings were treated at the Department of Physical Therapy and Rehabilitation, Hai Phong Traditional Medicine Hospital, from November 2025 to March 2026. According to traditional medicine classification, the patients were diagnosed with Bi syndrome (wind–cold–damp type) combined with liver–kidney deficiency. Method: A prospective interventional clinical study was conducted using a before-and-after comparison design without a control group. Results: The mean age of the study group was 71,80 ± 7,68 years, with the highest prevalence observed in individuals aged over 70 years. The female-to-male ratio was 76,7% to 23,3%. The majority of patients were engaged in manual labor (63,3%). The proportion of patients with unilateral knee involvement was 36,7%, while bilateral knee involvement accounted for 63,3%. Grade I obesity was observed in 46,7% of patients. The combined intervention of electroacupuncture and short-wave therapy demonstrated therapeutic efficacy in patients with knee osteoarthritis. The mean VAS pain score decreased by 3,00 ± 0,51 points after treatment. Knee joint range of motion increased by 14,59 ± 2,75 degrees. The severity of knee osteoarthritis, as assessed by the Lequesne, index decreased by 5,80 ± 1,10 points following treatment. The heel-to-buttock distance increased by 8,14 ± 2,58 cm after treatment. This combined treatment modality was found to be safe for patients. Conclusion: The combination of electroacupuncture and short-wave therapy is effective in patients with knee osteoarthritis, contributing to pain reduction and improvement in joint mobility.
Results of all-inside arthroscopic anterior cruciate ligament reconstruction using autologous gracilis and semitendinosus tendon grafts at Duc Giang General Hospital
Objective: To evaluate the outcomes of all-inside arthroscopic anterior cruciate ligament (ACL) reconstruction using autologous gracilis and semitendinosus tendon grafts at Duc Giang General Hospital. Subjects and Methods: This study included 33 patients aged 18–60 years with ACL rupture who underwent all-inside ACL reconstruction using autologous gracilis and semitendinosus tendon grafts at Duc Giang General Hospital from January 1, 2024, to December 31, 2024. Results: The mean operative time was 55.22 ± 6.82 minutes. The mean graft diameter was 8.77 ± 0.50 mm, and the mean graft length was 60.33 ± 1.88 mm. Rotational knee stability was well restored, with 93.3% of patients showing a negative pivot-shift test and 6.7% showing grade 1 positivity at 12 months postoperatively. At 12 months, no patients had limitations in knee extension or flexion. Postoperative knee function improved significantly: the mean Lysholm score at ≥12 months was 92.41 ± 3.65 in 30 patients, with 40% achieving good outcomes and 60% achieving excellent outcomes. The improvement in Lysholm scores before and after surgery was statistically significant. Conclusion: All-inside arthroscopic ACL reconstruction using autologous gracilis and semitendinosus tendon grafts is a minimally invasive technique that preserves bone stock, reduces postoperative pain, and shortens recovery time. Clinical and functional outcomes were rated good to excellent in over 90% of patients, comparable with those reported in national and international studies.
Study on monosensitization and polysensitization determined by specific ige quantification in allergic patients at Allergy clinic, Hai Phong Medicine University Hospital in 2025
Objective: To describe the clinical characteristics of allergic patients with monosensitization and polysensitization at Hai Phong Medicine University Hospital in 2025, and to compare total serum IgE levels between these two sensitization groups. Subjects and Methods: A cross-sectional descriptive study was conducted on 55 allergic patients at Hai Phong Medicine University Hospital from June 2025 to December 2025. Results: Polysensitization was more prevalent than monosensitization (83.64% vs. 16.36%). Patients with polysensitization exhibited more diverse and severe clinical manifestations, with symptoms such as angioedema (8.70%), dyspnea (15.22%), and gastrointestinal symptoms observed exclusively in this group. Total serum IgE levels were significantly higher in the polysensitized group than in the monosensitized group (median: 118 IU/mL vs. 34 IU/mL; p = 0.001). Conclusions: Polysensitization was associated with higher total serum IgE levels and more diverse, severe multisystem clinical manifestations compared with monosensitization.
Attention-deficit/hyperactivity disorder status among children with autism spectrum disorder at several educational centers in Phu Tho Province
Objective: To describe the status attention-deficit/hyperactivity disorder among children with autism spectrum disorder attending inclusive education centers in Phu Tho province. Methods: A cross-sectional descriptive study was conducted on 50 children diagnosed with autism spectrum disorder attending inclusive education centers from November 2025 to February 2026. Results: Mean age of the children was 7,8 years, and 84% were male. Attention-deficit/hyperactivity disorder was the most common comorbidity with a prevalence of 60%. On the Vanderbilt scale, the prevalence of inattention symptoms was 64%, while 36% had symptoms of hyperactivity/impulsivity. Correlation analysis showed a strong positive correlation between the ABC scores and Vanderbilt scores (ρ = 0,801; p < 0,001). Multivariable regression analysis showed that age (B = 1,758; p = 0,011) and the comorbidities (B = 10,908; p = 0,007) were independent predictors of a high total Vanderbilt score. Conclusion: Children with autism spectrum disorder have a high rate of comorbid attention-deficit/hyperactivity disorder, with the predominantly inattentive presentation being the most common. These findings highlight the importance of early detection of attention-deficit/hyperactivity disorder in the management and intervention for children with autism spectrum disorder.
The value of ultrasonography in the diagnosis of acute appendicitis at Hai Phong Medical University Hospital
Appendicitis is a common surgical emergency that can lead to serious complications if not diagnosed promptly. Ultrasonography serves as a pivotal diagnostic modality in the evaluation of acute appendicitis. Study objectives: Evaluation of the Diagnostic Value of Ultrasonography for Acute Appendicitis at Hai Phong University of Medicine and Pharmacy Hospital. This retrospective cross-sectional study included 190 patients with clinical suspicion of acute appendicitis who underwent abdominal ultrasonography and subsequent postoperative histopathological confirmation. The mean age of the cohort was41.7 ± 18.3 years (38.4% male, 61.6% female). The most prevalent ultrasonographic features were the "finger-like" sign (97.4%), non-compressible appendix (96.3%), increased diameter (94.7%), intraluminal fluid (93.7%), and periappendiceal fat stranding (87.9%). Ultrasonography exhibited high diagnostic performance for acute appendicitis, yielding a sensitivity of 97.4% and a positive predictive value (PPV) of 100%. In diagnosing appendiceal complications, the sensitivity, specificity, PPV, and negative predictive value (NPV) were 71.4%, 98.9%, 71.4%, and 98.9%, respectively.
Prevalence of menstrual disorders and traditional medicine syndrome patterns among six-year full-time female medical students: a cross-sectional study at Hai Phong University of Medicine and Pharmacy
Objectives: To investigate the prevalence of menstrual disorders (MD) and evaluate their corresponding Traditional Medicine (TM) syndrome classifications among female students enrolled in the 6-year full-time program at Hai Phong University of Medicine and Pharmacy from September 2025 to March 2026. Subjects and Methods: A cross-sectional descriptive study was conducted among 6-year full-time female medical students. Participants completed a standardized, self-administered research questionnaire. Students screening positive for MD underwent subsequent clinical evaluation and TM syndrome differentiation. Results: Out of 422 surveyed students, the overall prevalence of menstrual disorders was 42.7% (MD = 180 students). According to the FIGO-AUB 1 system (2018), specific cycle and flow abnormalities included: infrequent menstruation (cycle >38 days) at 10.0%, frequent menstruation (cycle <24 days) at 8.3%, scanty menstruation at 11.0%, heavy menstruation at 2.4%, and prolonged menstruation (>8 days) at 2.1%. The most prevalent perimenstrual symptoms reported were lower abdominal pain (80.1%), fatigue (66.4%), and irritability (57.8%). Within the cohort of students diagnosed with MD (n = 180), TM disease classification revealed: Oligomenorrhea 26.1%, Delayed Menstruation 23.3%, Irregular Menstrual Cycle 20.6%, Early Menstruation 19.4%, Polymenorrhea: 5.6%, Prolonged Menstruation: 5.0%. TM syndrome differentiation identified the leading clinical subtypes as: Liver Qi Stagnation: 35.6%. Qi Deficiency: 26.7%. Blood Deficiency: 18.3%, Other subtypes: Phlegm-Dampness (10.0%), Blood Stasis (4.4%), Blood Heat (2.8%), and Kidney Deficiency (2.2%). Conclusions: Female medical students in the intensive 6-year curriculum exhibit a high prevalence of menstrual disorders (42.7%), characterized primarily by cycle irregularities and oligomenorrhea. The predominance of the Liver Qi Stagnation syndrome strongly suggests that psychological stress and emotional disharmony inherent to rigorous medical training are primary contributing factors to neuroendocrine-menstrual dysfunction in this cohort.
The quality of life of pediatric patients with diabetes at Hai Phong Children's Hospital in 2022 – 2024
Objectives: To describe characteristics and factors related to the quality of life (QoL) of patients with diabetes treated at Hai Phong Children's Hospital. Subjects: 41 diabetic patients under observation and treatment from December 3rd, 2022, to September 30th, 2024, at Hai Phong Children’s Hospital. Methods: A descriptive study was conducted on 41 pediatric children with diabetes treated at Hai Phong Children’s Hospital from 03/12/2022 to 30/09/2024. Results: The 8–12 age group was most prevalent (48.8%). The male-to-female ratio was 1.16:1, and the rural-to-urban ratio was 1.7:1. Notably, 55.26% of patients maintained good academic standing. The mean age of onset was 123,73 ± 45,75 months. Most patients (87.8%) had been living with the disease for less than 5 years. Lower QoL scores were significantly associated with lower parental education levels compared to higher parental education levels (p < 0.01). Children with type 1 diabetes tend to have lower QoL scores compared to those with type 2 (p < 0.05). QoL was significantly lower in patients with a history of inpatient treatment within the last 6 months, those with existing complications, and those with poor glycemic control (p < 0.01). Conclusion: The decreased QoL in children with diabetes is associated with factors such as lower parental education, type 1 diabetes, the presence of complications, uncontrolled blood glucose, and recent hospitalizations.
Surgical outcomes of gallbladder cancer at Bach Mai Hospital, 2024-2025
Objectives: To evaluate the surgical outcomes of gallbladder cancer at Bach Mai Hospital. Subjects and methods: This retrospective descriptive study included 29 patients with histopathologically confirmed gallbladder cancer who underwent surgical treatment at Bach Mai Hospital from January 1, 2024 to December 31, 2025. Results: The mean age was 68.86 ± 12.96 years, ranging from 37 to 94 years. The female-to-male ratio was 1.2:1. The most common clinical symptom was abdominal pain, accounting for 79.3%, while jaundice was observed in 17.2% of patients. According to the AJCC staging system, stage II accounted for the highest proportion, at 44.8%, followed by stage IVB at 20.7%. Simple cholecystectomy was the most frequently performed surgical procedure, accounting for 51.7%; cholecystectomy combined with resection of the invaded hepatic subsegment accounted for 41.4%; and palliative surgery accounted for 6.9%. Hepatoduodenal ligament lymphadenectomy was performed in 44.8% of patients, and lymph node metastasis was recorded in 13.8% of the total cohort. The R0 resection rate was 82.8%. Postoperative chemotherapy was administered to 24.1% of patients. Postoperative complications occurred in two cases; the discharge rate was 96.6%, and postoperative mortality was 3.4%. The mortality rate during follow-up was 13.8%. Disease-free survival and overall survival tended to differ across AJCC stages, but the differences were not statistically significant by the log-rank test, with p > 0.05. Conclusion: Gallbladder cancer in this study mainly occurred in older patients, with nonspecific clinical manifestations, and most patients were managed surgically. Early postoperative outcomes were relatively favorable, particularly among patients who achieved R0 resection. Early detection, adequate assessment of nodal status, and consideration of postoperative adjuvant therapy are important for improving prognosis.
Clinical and paraclinical characteristics and factors associated with adherence to outpatient treatment among patients with chronic obstructive pulmonary disease at Hai Phong Lung Hospital 2025 - 2026
Objectives: To describe the clinical and paraclinical characteristics and to analyze factors associated with treatment adherence among patients with chronic obstructive pulmonary disease (COPD) managed as outpatients at Hai Phong Lung Hospital from December 2025 to February 2026. Subjects: A total of 269 COPD outpatients from two COPD management clinics at Hai Phong Lung Hospital who met the inclusion criteria were enrolled in the study. Methods: A cross-sectional study design was used. Results and Conclusions: The majority of patients were male (88.1%), mean age of 67,6 ± 7,3 years. Hypertension was the most common comorbidity (32.3%). Dyspnea of varying severity was the most frequent symptom (96.4%). The overall treatment adherence rate was 82.5%. Most patients were classified as GOLD stages 2 and 3 (73.6%). The proportion of patients with eosinophil counts ≥300 cells/mm³ was 48.7%. Chest X-ray findings were predominantly emphysema (71.7%). Factors associated with treatment adherence included: education level of high school or higher (OR = 2.7; p = 0.021), low concern about medication side effects (OR = 2.9; p = 0.006), COPD duration greater than 5 years (OR = 2.5; p = 0.006), and mMRC score ≥ 2 (OR = 2.2; p = 0.049). Mild to moderate depression was associated with reduced treatment adherence (p < 0.05). Other factors showed no statistically significant association with outpatient COPD treatment adherence.
Current status and factors associated with knowledge, attitudes, and practices regarding sexually transmitted infections among final-year medical students at Hai Phong University of Medicine and Pharmacy
Objectives: This study describes the current situation and some related factors concerning knowledge, attitudes, and practices regarding sexually transmitted diseases among final-year medical students at Hai Phong University of Medicine and Pharmacy. Methods: This is a descriptive cross-sectional study involving interviews with 335 final-year medical students using pre-prepared questionnaires at Hai Phong University of Medicine and Pharmacy from October 2025 to February 2026. The assessment tool consists of three parts: knowledge (multiple-choice questions, true/false scoring), attitude (5-point Likert scale), and practice (frequency of behavior with 3 levels). The total score for each part is standardized and classified into corresponding evaluation levels. Results: The percentages of students with satisfactory knowledge and positive attitudes and correct practices were 87.7%, 73.7%, and 62.1%, respectively. Age was related to knowledge; while attitudes and practices were influenced by academic major, sharing with family, relationship status, and sexual behavior. Conclusion: Final-year medical students have relatively good knowledge and attitudes regarding STIs; however, their preventive practices are not commensurate, reflecting a gap between awareness and behavior. Health education programs need to be developed that focus on behavioral change, not just providing knowledge.
Outcomes of electrosurgical treatment for low-attached maxillary labial frenum in children (2025–2026)
This study aimed to evaluate the outcomes of electrosurgical frenectomy for low-attached maxillary labial frenum in pediatric patients. A non-controlled interventional clinical study was conducted on 35 children with class II and III low-attached maxillary labial frenum at Hai Phong Children’s Hospital from October 2025 to April 2026. All patients underwent frenectomy using electrosurgery under general anesthesia and were followed up for anatomical characteristics and postoperative complications. The results showed that the mean frenulum height and thickness were 7.76 ± 1.24 mm and 0.89 ± 0.11 mm, respectively, with significantly higher values in class III compared to class II (p < 0.05). During surgery, most patients had no bleeding (77.1%), while the remaining cases showed only mild oozing, with no severe bleeding recorded. Postoperative bleeding was rapidly controlled, with 100% of patients free of bleeding after 6 hours. Pain and swelling were mostly mild and gradually decreased over time, with complete resolution observed from day 7 to day 21. No severe complications were reported; only 6.7% of cases experienced mild postoperative fever, which resolved spontaneously. The findings suggest that electrosurgical frenectomy is a safe, effective, minimally invasive method with rapid recovery and a low complication rate in children.
Comparison of the outcome of endotracheal intubation using video laryngoscope and Macintosh laryngoscope at Hai Phong University of Medicine Hospital, 2025
Objective: Comparison of the outcome of endotracheal intubation using video laryngoscopy (VL) compared with direct laryngoscopy using the Macintosh blade (DL) in patients undergoing general anesthesia at Hai Phong University Hospital from April 2025 to October 2025. Methods: This was a prospective, randomized, comparative study conducted on 60 adult patients classified as ASA I–III who required endotracheal intubation under general anesthesia. Patients were randomly assigned into two equal groups: the video laryngoscope group (VL, n = 30) and the direct Macintosh laryngoscope group (DL, n = 30). Results: The first-attempt success rate of endotracheal intubation was 96.7% in the VL group, significantly higher than 80.0% in the DL group (p = 0.04). The proportion of patients with a Cormack–Lehane grade I–II view was 93.3% in the VL group versus 70.0% in the DL group (p = 0.02). The mean number of intubation attempts was significantly lower in the VL group (1.07 vs. 1.33; p = 0.01). The rate of airway mucosal injury was 3.3% in the VL group and 20.0% in the DL group (p = 0.04). No severe complications were recorded in either group. Conclusion: Video laryngoscopy improves visualization of the glottis, increases first-attempt intubation success, and reduces airway trauma compared with direct Macintosh laryngoscopy. Video laryngoscopy is an effective and safe airway management tool and should be encouraged for routine use in anesthetic practice, particularly in patients at risk of difficult airway.
Characteristics of Bacterial Pathogens and Treatment Outcomes in Children with Community-Acquired Pneumonia at Hai Phong Children's Hospital
Objective: To describe the characteristics of bacterial pathogens and evaluate the treatment outcomes of community-acquired pneumonia (CAP) in pediatric patients aged 2 months to 5 years at Voluntary Department A, Hai Phong Children's Hospital, from January 1 to December 31,2024. Subjects: 98 pediatric patients diagnosed with community-acquired pneumonia who had positive nasopharyngeal culture and underwent antimicrobial susceptibility testing, treated at the Voluntary Department A, Hai Phong Children's Hospital, 2024. Methods: A retrospective, descriptive cross-sectional study. Results: Severe pneumonia was diagnosed in 78.57% of the pediatric patients. The three most common bacterial pathogens causing community-acquired pneumonia were Haemophilus influenzae (38.78%), Moraxella catarrhalis (29.59%), and Streptococcus pneumoniae (23.47%). Prior to the availability of antimicrobial susceptibility testing results, the most frequently utilized empiric antibiotic regimens were third-generation cephalosporins+ aminoglycosides (43.88%), third-generation cephalosporins alone (26.53%), and penicillin+aminoglycosides (23.47%). Following the receipt antimicrobial susceptibility testing results, the most common antibiotic regimens adjusted were third-generation cephalosporins+quinolones (48.34%), third-generation cephalosporins+aminoglycosides (25.06%), and penicillin+quinolones (20%). The mean duration of treatment for the study subjects was 9.17 ± 3 days, with a recovery rate of 90.82%. Conclusion: H. influenzae, M. catarrhalis, and S. pneumoniae are the most common pathogens causing community-acquired pneumonia in children aged 2 months to 5 years. These bacteria exhibited high susceptibility rates to third-generation cephalosporins and quinolones. The overall patient recovery was 90.82%.
Quality of Life After Hip Arthroplasty in Patients With Chronic Hip Diseases: A Longitudinal Study
Objective: To evaluate the quality of life of patients with chronic hip diseases after hip replacement surgery at Viet Tiep Friendship Hospital, Hai Phong, in 2021. Subjects and Methods: A longitudinal study was conducted on 37 patients with chronic hip diseases who underwent hip arthroplasty at Viet Tiep Friendship Hospital. Quality of life was assessed using the Vietnamese version of the 36-Item Short-Form Health Survey (SF-36) before surgery and at 1–1.5 months postoperatively. Data were analyzed using SPSS version 13.0. Results: The mean overall quality-of-life score increased significantly from 43.9 ± 1.9 before surgery to 78.9 ± 8.2 at 1–1.5 months after surgery (p < 0.05). Significant improvements were observed across all eight domains of physical and mental health following surgery (p < 0.05). Conclusion: Quality of life improved significantly during the early postoperative period following hip arthroplasty in patients with chronic hip diseases.
Dominant Handgrip Strength and Associated Factors among Preventive Medicine Students at Hai Phong University of Medicine and Pharmacy in 2024
A cross-sectional study was conducted to describe dominant handgrip strength and associated factors among preventive medicine students at Hai Phong University of Medicine and Pharmacy in 2024. The study, involving 187 students, found that 82.9% did not meet the criteria for adequate dominant handgrip strength. Among males, the mean dominant handgrip strength was 45.5 ± 2.9 kg in the adequate group and 35.0 ± 5.1 kg in the inadequate group. Among females, the corresponding values were 32.14 ± 5.8 kg and 21.0 ± 2.9 kg, respectively. The overall mean dominant handgrip strength was 38.7 ± 6.8 kg for males and 21.8 ± 4.4 kg for females. The prevalence of inadequate handgrip strength was 64.6% in males and 92.6% in females. Independent factors associated with inadequate dominant handgrip strength included female sex and insufficient physical activity, with odds ratios (95% CI) of 3.04 (1.15–8.02) and 3.75 (1.38–10.12), respectively (p < 0.05). It is recommended to strengthen physical activity interventions among students to improve handgrip strength, as well as to conduct periodic handgrip strength assessments for a more comprehensive evaluation of student health.
Clinical, paraclinical characteristics and treatment results of patients with pneumothorax at Hai Phong Lung Hospital 2023 – 2025
Background: Pneumothorax is a medical emergency that requires prompt management. If inadequately treated, it may lead to severe complications and even death. Objective: To describe the clinical, paraclinical characteristics and treatment results of patients with pneumothorax at Hai Phong Lung Hospital 2023 - 2025. Subjects and Methods: A combined retrospective and prospective descriptive study on 100 pneumothorax patients treated at Hai Phong Lung Hospital from January 2023 to December 2025. Results: The mean age of the patients was 54.9 ± 16.8 years, males accounted for 92.0%. Spontaneous pneumothorax accounted for 97.0% (primary 47.0% and secondary 50.0%). The proportion of patients with a history of tuberculosis treatment or active pulmonary tuberculosis, COPD, smoking, and a history of pneumothorax were 36.0%, 22.0%, 42.0%, and 17.0%, respectively. Common symptoms included dyspnea (100%), chest pain (95.0%), cough (95.0%) and Galliard's triad (90.0%). Chest X-ray and CT scan showed a large pneumothorax (75.0%), emphysema (64.6%), cavitary lesions (10.8%), and bullae (36.9%). The main treatment method was needle aspiration or chest tube drainage (81.0%). The rate of complete lung re-expansion at discharge was 85.0% (oxygen therapy 84.2% and drainage/aspiration 85.2%). The time to complete re-expansion via drainage/aspiration was significantly shorter than with oxygen therapy (3.48 ± 3.2 vs. 6.38 ± 3.4 days, p < 0.01). Conclusion: Pneumothorax was commonly observed in patients aged 50 years and older, predominantly as spontaneous pneumothorax. Most patients with secondary spontaneous pneumothorax had a history of COPD, pulmonary tuberculosis, or smoking. The main treatment modality was aspiration/drainage, which achieved a higher rate of pneumothorax resolution and a shorter time to resolution compared with oxygen therapy.
Knowledge about Practice of Insulin Injection among Diabetic Patients at the Outpatient Department – Hai Phong University of Medicine and Pharmacy Hospital 2025-2026
Objective: To describe the current status of treatment adherence among hypertensive patients receiving outpatient care at the Outpatient Department of Hai Phong University of Medicine and Pharmacy Hospital in 11/2025-01/2026. Subjects and Methods: This is a descriptive cross-sectional study design, conducted on 116 diabetic patients managed and treated at the Outpatient Department of Hai Phong University of Medicine and Pharmacy Hospital in 11/2025-01/2026; To assess the knowledge of insulin injection technique among diabetic patients using the 'Injection Technique Questionnaire' (ITQ). Results: The mean age was 64.30 ± 12.60 years; the male-to-female ratio was 50.86% to 49.14%; and the majority of participants had a high school education or higher, accounting for 78.45%. Regarding correct knowledge: storage of unused insulin (87.93%); warming insulin before injection (84.48%); expiration time after opening (90.52%); timing of meals post-injection (98.28%); identifying spoiled insulin (84.48%); recognizing symptoms of hypoglycemia (81.90%); proper management of hypoglycemia (87.07%); effects of current insulin types (79.31%); storage of in-use insulin (64.66%); and injection site rotation (90.52%). Knowledge of insulin administration practices: hand hygiene before injection (85.35%); mixing/agitating insulin before use (82.76%); injection site selection (87.07%); site disinfection (87.93%); injection technique (88.79%); needle disposal after use (90.52%); and identifying injection site abnormalities (74.14%). Regarding delivery devices, 38.79% used insulin pens and 61.21% used syringes; the correct medication preparation rate was 100% for pen users and 87.32% for syringe users. Conclusions and Recommendations: The proportion of patients with high levels of insulin knowledge about practical injection knowledge was significant; The rate of patients with knowledge of injection technique was higher in the pen group compared to the syringe group. Further longitudinal research is needed to explore the link between knowledge and practice in Insulin-treated patients with diabetes. Health education should be intensified, and the use of insulin pens prioritized where feasible.
Clinical and radiological characteristics of patients with thoracolumbar spine trauma at Ha Tinh Provincial General Hospital
Objective: To describe the clinical and radiological characteristics of patients with thoracolumbar spine trauma at Ha Tinh Provincial General Hospital. Subjects and Methods: This was a descriptive case series study with both retrospective and prospective data collection, including 106 patients with thoracolumbar spine trauma who underwent surgical treatment at Ha Tinh Provincial General Hospital from January 2023 to February 2026. Results: Thoracolumbar junction injuries were predominantly caused by domestic accidents (54.8%). The male-to-female ratio was 1.3:1, with a mean age of 53.27 ± 12.85 years. The most commonly affected vertebral level was L1 (49.6% on X-ray and 44.1% on CT), followed by D12 (27.4% and 26.5%, respectively). Conclusion: Spinal CT plays a decisive role in the accurate diagnosis of injuries, allowing detailed assessment of fracture morphology. It is superior to plain radiography in detecting subtle lesions and multilevel injuries.
In silico screening of natural compounds from medicinal plants as potential VEGFR2 inhibitors
This study aimed to construct a database of natural compounds derived from essential traditional medicinal plants with potential inhibitory activity against hepatocellular carcinoma (HCC), and to evaluate their interactions with vascular endothelial growth factor receptor 2 (VEGFR2) using molecular docking simulations. Through a selective literature review combined with in silico screening, a total of 37 compounds with well-defined chemical structures and relevant biological activities were identified and analyzed. Docking results indicated that all compounds were capable of binding to VEGFR2, with binding energies ranging from –3.18 kcal/mol (Neoprzewaquinone A) to –11.89 kcal/mol (Liensinine), with the majority exhibiting moderate to strong binding affinity. Notably, liensinine, an alkaloid isolated from Nelumbo nucifera Gaertn., demonstrated the lowest binding energy, suggesting a stable interaction with VEGFR2. These findings highlight that natural compounds derived from traditional medicinal plants, particularly liensinine, represent promising candidates for the development of anti-HCC agents and warrant further investigation through experimental studies and advanced computational approaches.
Researching the manufacturing process of traditional medicine granules derived from the 'Tang cúc ẩm' formula
Objective: To develop a manufacturing process for granules based on the traditional herbal formula “Tang Cúc Ẩm” and to evaluate selected quality parameters of the finished product. Methods: Medicinal materials were extracted by decoction and steam distillation; the extract was purified using 96% ethanol. The granules were prepared by the wet granulation method. The quality of the final product was evaluated in accordance with the Vietnamese Pharmacopoeia V. Results: An optimal formulation was selected using lactose as a diluent (400 g per 100 mL of concentrated extract), with the herbal extract itself serving as the binder. The resulting granules had a moisture content of 1.37%, a disintegration time of 1.26 minutes, and an average amygdalin content of 0,66%. Conclusion: A formulation and manufacturing process for granules derived from the traditional medicine formula “Tang Cuc Am” were developed. The prepared product met the required criteria for appearance, disintegration time, moisture content, and mass uniformity according to the standards of the Vietnamese Pharmacopoeia V.
In utero electroporation technique and its applications in modern neuroscience research: A review
In utero electroporation (IUE) is an advanced, powerful technique used to transfer gene fragments (DNA, RNA, siRNA) into neural progenitor cells in the brain of mouse embryos (or other experimental animals) while still in the uterus. It is not yet widely applied in biomedical research in Vietnam. This literature review aimed to introduce the basic procedure of IUE and some potential applications in research conducted in Vietnam. Methods: References were collected and analyzed using the keyword “in utero electroporation” to filter relevant documents on the platform https://pubmed.ncbi.nlm.nih.gov/. The inclusion criteria for the literature selection were as follows: (i) original research articles or peer-reviewed review articles; (ii) studies directly relevant to the research topic; and (iii) articles providing data or analyses with clear scientific value. Results: Through the review of 42 publications on IUE, we have clarified the basic requirements for materials, equipment, and IUE technical procedures, as well as some research applications of this technique in neuroscience research, especially developmental neuroscience. Conclusion: IUE is an effective and easily implemented technique in research on the formation and function of the central nervous system.
Clinical Epidemiology of Haemophilus influenzae Pneumonia in Children Aged 12 Months to 15 Years at Hai Phong International Obstetrics and Pediatrics Hospital, 2024–2025
Objective: To describe the clinical and paraclinical characteristics of H. influenzae pneumonia in children aged 12 months to 15 years at the Respiratory–Cardiology Department, Hai Phong International Obstetrics and Pediatrics Hospital from October 1, 2024 to September 30, 2025 and assess the antibiotic susceptibility of H. influenzae based on antibiogram results. Methods: A descriptive study on 41 children aged 12 months to 15 years diagnosed with H. influenzae pneumonia. Results: The disease mainly occurred in children aged 1–5 years (90.2%), with a male predominance. Common symptoms included cough (100%), fever (68.3%), lung crackles (92.7%), and tachypnea (68.3%). Chest X-ray commonly showed perihilar opacities (48.8%). Leukocytosis was present in 75.6%, and elevated CRP in 51.2%. H. influenzae remained highly sensitive to carbapenems and third-generation cephalosporins but showed high resistance to cefixime (80.5%), ampicillin/sulbactam (73.2%), and azithromycin (63.4%). Conclusion: Pediatric H. influenzae pneumonia shows typical clinical features with notable antibiotic resistance, highlighting the need for rational antibiotic use
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A case review: Rectal gist at Viettiep Hospital
GIST (Gastro-intestinal Stromal Tumor) are the most mesenchymal tumors of the gastrointestinal tract-usually happened at stomach, bowel and rarely at colon, rectum. They account only approximately 3-5% at rectum. Previously, these tumors have been referred to as leiomyoma, leiomyosarcoma, leiomyoblastoma, gastrointestinal autonomic nerve sheath tumor (GANT), and gastrointestinal pacemaker cell tumor (GIPACT) as they were difficult to differentiate on histopathology until a characteristic expression of c-KIT (CD117) was identified. These tumors are diagnosed by histopathology and immunohistiochemistry. In this paper, we report a case of rectal GIST was diagnosed and cure at Viettiep Hospital. The patient is a man, 35 years old, who was admitted Viettiep Hospital with symptoms of tenesmus without blood stool. The patient was examined by MRI. The result is as follow: The tumors is beside the left of rectum. Its size is 5.3x5.4x5.8cm with intermediate signal in T1W, T2W. It is hyperintensity in T2 fatsat and high signal DWI and low ADC with value is 0.76 x10-3 mm2/s. Tumor enhanced homogenously after MRI contrast agent injection. Although the tumors size is big, more than 5cm but histopathology is low grade GIST. The patient was rectectomy with tumor. In conclusion rectal GIST is rare. but diagnostic imaging plays an importan role. It can help for positive diagnose and especially it is also evaluation relative between tumor and other factors which help the clinical doctors can choose the best methode to cure.
Copyright (c) 2026 Tạp chí Khoa Học Sức Khỏe
Results of treatment of benign prostate hyperplasia by monopolar turp at Hai Phong University Of Medicine Hospital
Objective: To describe the results of treatment of benign prostatic hyperplasia by endoscopic urethral resection with monopolar electrocautery at Hai Phong University of Medicine Hospital. Subjects and Methods: This descriptive study included 31 patients treated for benign prostatic hyperplasia (BPH) via transurethral endoscopic resection with monopolar electrocautery at Hai Phong University Medical Center from January 2024 to June 2025. Results: The average age was 69.8 ± 7.6 (57 ÷ 82) years. The average prostate volume was 49.8 ± 2.7 ml. The surgical time was 40.8 ± 12.7 (19 ÷ 70). Postoperative complications were rare: 2/31 (6.5%). The majority of patients were hospitalized for 4-5 days after surgery (45.1% and 38.7% respectively). Conclusion: Treatment of benign prostatic hyperplasia via transurethral endoscopic resection with monopolar electrocautery is a safe, effective method with few complications.
Endoscopy, histopathology, and the relationship with the incidence of helicorbacter pylori infection in patients with chronic gastritis at Hai Phong Medical University Hospital 2024-2025
Objective: To describe endoscopic and histopathological images in patients with chronic gastritis. To examine the relationship between endoscopic and histopathological results and the prevalence of Helicobacter Pylori (H.pylori) infection in the study subjects at the Endoscopy Department of Hai Phong Medical university Hospital from December 2024 to April 2025. Subjects and methods: A cross-sectional descriptive study was conducted on 227 patients diagnosed with chronic gastritis via endoscopy, who underwent H.pylori testing (CLO test) and histopathology at the Endoscopy Department of Hai Phong Medical university Hospital from December 2024 to April 2025. Results: The female/male ratio was 1.2/1, with a higher incidence in the age group of 16-29 years (36.1%). The ratio of patients with the disease to urban/rural areas was 2/1, and they were mainly civil servants and laborers (48.5%). The most common endoscopic findings were inflammatory lesions in the antrum with edema and hyperemia (41.9%). Histopathological findings were atrophic gastritis/superficial inflammation in the antrum (63.4%/36.6%). The prevalence of Helicobacter pylori infection was 66.5%. There was a statistically significant correlation between H.pylori infection and endoscopic findings (95% CI: 1.9-6.9; p < 0.05). A correlation was also observed between gastric mucosal atrophy on histopathology and H.pylori infection rate (95% CI: 2.2-6.4; p < 0.05). Conclusion: The disease affects both men and women with a female/male ratio of 1.2/1. There were no differences in age group or geographical/occupational factors. The prominent lesions observed on endoscopy were edema and hyperemia. Atrophic gastritis was the most common histopathological lesion. High rates of H. pylori infection are associated with a high incidence of physical lesions on endoscopy and gastric mucosal atrophy.
Knowledge and attitude of nurses on fall prevention for patients at Hai Phong University of Medicine Hospital in 2025
Objectives: To describe the current state of Nurses’s knowledge, attitude regarding fall prevention for patients at Hai Phong University Medical hospital in 2025 and to identify some related factors. Methods: A cross-sectional descriptive study was conducted on 101 nurses working in clinical departments at Hai Phong University Medical Hospitạl. Resullt: The results showed that 75,2% of nurses had satisfactory knowledge about fall prevention. 76,2% of nurses had a positive attitude towards fall prevention. Nurses with satisfactory knowledge had a higher positive attitude than nurses with inadequate knowledge (p < 0,05). Nurses who receive training on fall prevention had a higher positive attitude than nurses who do not receive fall prevention training (p<0,05). Conclusion: The knowledge and attitudes of nurses regarding fall prevention for patients are not high. Nurses with adequate knowledge and training in fall prevention when they start working at the hospital have a more positive attitude than nurses with inadequate knowledge and less positive attitudes.