Standardised flavonoid extract from Diospyros kaki L.f leaves alleviates high blood pressure and ventricular hypertrophy on cortisone acetate-induced hypertensive rats

  • Thi Thanh Loan Nguyen, Thi Van Anh Pham, Thi Xoan Le*
Từ khóa: angiotensin-converting enzyme inhibitor, anti-hypertensive effect, Diospyros kaki L.f leaves, ventricular hypertrophy.

Tóm tắt

The current study was designed to investigate the anti-hypertensive effects of a standardised flavonoid extract from Diospyros kaki L.f leaves (DK extract) on cortisone acetate-induced hypertensive rats. Hypertension was induced in Wistar rats by subcutaneously injecting 2.5 mg cortisone acetate daily and by maintaining the rats on a 1% sodium chloride diet for a period of 28 days...

Tác giả

Thi Thanh Loan Nguyen, Thi Van Anh Pham, Thi Xoan Le*

Department of Pharmacology and Biochemistry, National Institute of Medicinal Materials, 3B Quang Trung, Trang Tien Ward, Hoan Kiem District, Hanoi, Vietnam
Department of Pharmacology, Hanoi Medical University, 1 Ton That Tung Street, Khuong Thuong Ward, Dong Da District, Hanoi, Vietnam

điểm /   đánh giá
Phát hành ngày
2023-09-15