Molecular docking and molecular dynamics simulation revealed potential compounds in Salvia miltiorrhiza for inhibiting enzymes and receptors in Alzheimer’s disease

  • Tung Bui Thanh*, Trang Vu Dai, Huong Le Thi
Từ khóa: Alzheimer, in silico, molecular docking, molecular dynamics, Salvia miltiorrhiza

Tóm tắt

Alzheimer’s disease is an age-related neurodegenerative disorder that leads to cognitive and functional decline. Potential target proteins for managing Alzheimer’s disease include Acetylcholinesterase (AChE), Butyrylcholinesterase (BuChE), Beta-secretase cleavage enzyme (BACE1) and N-methyl-D-aspartate (NMDA) receptors. In this study, we conducted in silico evaluations of the inhibitory effects of Salvia miltiorrhiza’s compounds on AChE, BuChE, BACE1, and NMDA receptors...

Tác giả

Tung Bui Thanh*, Trang Vu Dai, Huong Le Thi

Pharmacology Department, University of Medicine and Pharmacy, Vietnam National University - Hanoi, 144 Xuan Thuy Street, Dich Vong Hau Ward, Cau Giay District, Hanoi, Vietnam

điểm /   đánh giá
Phát hành ngày
2024-06-15
In ra
Số. 2C (2024): JUNE 2024 . VOLUME 66 NUMBER 2
Chuyên mục
LIFE SCIENCES