Assessment of the role of ultrasonic-guided fine needle aspiration cytology in diagnosis of differentiated thyroid cancers patients

Abstract

Background: Ultrasonic-guided fine needle aspiration cytology is a minimally invasive diagnostic technique with the highest accuracy and sensitivity in the diagnosis of lymph node metastasis.

Objectives: The study consists of 2 objectives: 1) Describe clinical and subclinical characteristics in treated patients with differentiated thyroid cancer; Evaluation of the role of ultrasound-guided fine needle aspiration cytology in the diagnosis of lymph node metastasis in patients with differentiated thyroid cancer.

Materials and methods: A cross-sectional descriptive study design was conducted on 89 patients diagnosed with differentiated thyroid cancer and found that the cervical lymph nodes were potentially malignant under ultrasonography and indicated fine-needle aspiration cytology under ultrasound guidance.

Results: Among 89 research subjects, small cell aspiration of lymph node groups, group IV and VI lymph nodes with suspicion of malignancy accounted for the highest proportion of 25/89 nodes (28.1%) fine needle aspiration cytology, in which positive accounts for 30.1%. Sensitivity, specificity, negative predictive value, false positive rate, false negative rate, and cytology accuracy were 90%; 100%; 100%; 52.9%.0%, 10.1%, 91.01%.

Conclusion: Ultrasonic-guided fine needle aspiration cytology for the diagnosis of lymph node metastasis in differentiated thyroid cancer has a low false-positive rate, high accuracy, accurately reflecting the presence or absence of underlying cervical lymph node metastasis. Avoid complications and thoroughly treat metastatic disease for patients.