Imaging characteristics and the role of whole body multidetector computed tomography in patients with stage IV prostate cancer

Abstract

Purpose: The study was conducted to describe image characteristics of prostate cancer on multidetector computed tomography (MDCT) and to determine the role of MDCT in patients with stage IV prostate cancer.

Objectives and subjects: A cross-sectional study was performed on 45 patients at Huu Nghi Hospital from January 2017 to May 2023. All patients had pathologically proven prostate cancer, multi-parameter magnetic resonance imaging (mp-MRI), MDCT, and bone scan and were categorized as stage IV.

Results: The mean age was 78.31±5.64 years, mean Total prostatespecific antigen (tPSA) concentration was 279.78 ng/ml, mean prostate volume was 45.20 ml. 60% of patients had extra-prostatic invasion, 66.7% had regional lymph node metastases; 40% of patients had distant lymph node metastasis; 46.7% had bone metastasis; 28.9% had distant metastasis to other organs. MDCT had good to very good concordance with MRI in evaluating local invasion and good concordance with bone scintigraphy in evaluating bone metastasis, with p <0.05.

Conclusion: MDCT had a high value in assessing metastatic lesions in patients with stage IV prostate cancer, especially lung lesions. Whole-body MDCT is a useful alternative to MRI and PET/CT in evaluating metastatic lesions from prostate cancer