The golden window for treating basedow eye disease and warning signs

Các tác giả

  • The Thanh Nguyen An Sinh Hospital; Nhan Dan Gia Đinh Hospital

Từ khóa

Thyroid Eye Disease, Graves’ Disease, Rundle’s Curve, Clinical Activity Score

DOI:

https://doi.org/10.47122/VJDE.2025.82.1

Tóm tắt

Background: Thyroid Eye Disease (TED) affects 13–69% of Graves’ patients, mainly in the hyperthyroid phase (90%) but also in euthyroid or hypothyroid phases (10%). The golden window (6–24 months) is crucial for preventing progression. Key points: Active Phase (6–24 months): Inflammation,  exophthalmos,  vision risk. Stable Phase: Symptoms persist but inflammation subsides. Early treatment (CAS ≥ 3) is essential: Smoking cessation, Selenium, NSAIDs, corticosteroids, immunosuppressants, Ophthalmologic management. Warning: TED symptoms and positive TRAb/TSI in euthyroid patients may predict Graves’ disease onset. Conclusion:  Early  intervention  within 24 months prevents severe outcomes. Monitoring elevated TRAb/TSI in euthyroid patients is key to early Graves’ diagnosis.

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Đã Xuất bản

2026-04-29

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