LEFT VENTRICULAR NONCOMPACTION CARDIOMYOPATHY WITH TRIPLE TTN VARIANTS MASQUERADING AS ARRHYTHMIA-INDUCED CARDIOMYOPATHY: A CASE REPORT

  • Lâm Thành Vĩ
  • Ngo Long Van
  • Tran Nguyen Thao Nhi
  • Nguyen Thanh Huan
DOI: https://doi.org/10.63947/bvtn.v1i5.20
Từ khóa: Left ventricular noncompaction cardiomyopathy, arrhythmia-induced cardiomyopathy, TTN gene

Tóm tắt

Left ventricular noncompaction cardiomyopathy (LVNC) can lead to ventricular arrhythmias and may be misdiagnosed as arrhythmia-induced cardiomyopathy (AiCM). While LVNC is associated with genetic abnormalities, AiCM is triggered by arrhythmias and is typically reversible once the arrhythmia is eliminated. We report the case of a 59-year-old woman with LVNC carrying three TTN gene variants: c.100804A>T (p.Met33602Leu, exon 358), c.59200C>G (p.Pro19734Ala, exon 300), and c.52052T>C (p.Val17351Ala, exon 273). The patient was initially diagnosed with AiCM but showed no recovery of left ventricular function after successful catheter ablation of ventricular arrhythmias. Echocardiography and cardiac magnetic resonance imaging confirmed the LVNC phenotype. This case highlights the importance of distinguishing between these two entities in clinical practice.

điểm /   đánh giá
Phát hành ngày
2025-11-01
In ra
Tập. 1 Số. 5 (2025): Thong Nhat Hospital’s 50-Year Journey - Comprehensive Healthcare and Healthy Aging
Chuyên mục
Case Report

Bản quyền (c) 2025 Tác giả. Xuất bản bởi Tạp chí Sức khỏe và Lão hóa.

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