DETERMINATION OF DIOXIN-LIKE POLYCHLORINATED BIPHENYL IN PIG FEED BY GAS CHROMATOGRAPHY TRIPLE QUADRUPOLE MASS SPECTROMETRY IN COMPARISON WITH HIGH-RESOLUTION GAS CHROMATOGRAPHY/HIGH-RESOLUTION MASS SPECTROMETRY

Tóm tắt

This study evaluates and compares the performance of gas chromatography triple quadrupole mass spectrometry and high-resolution gas chromatography/high-resolution mass spectrometry for determining dioxin-like PCBs (dl-PCBs) in pig feed. The gas chromatography triple quadrupole mass spectrometry method exhibited strong analytical performance, with limits of detection ranging from 0.03 to 0.05 pg/g and recovery efficiencies between 89% and 103%. It demonstrated good repeatability, reproducibility, and accuracy. Most toxic dioxin-like polychlorinated biphenyl congeners were found in all feed samples, except PCB#81 in P1 and PCB#157 in P2 and P3. The total toxic equivalent values ranged from 0.019 to 0.039 pg TEQ/g. The toxic equivalent results obtained by gas chromatography triple quadrupole mass spectrometry were in close agreement with those from high-resolution gas chromatography/high-resolution mass spectrometry, with relative percent differences generally below 10%, indicating high method concordance. These findings confirm that of gas chromatography triple quadrupole mass spectrometry is a reliable and efficient alternative to high-resolution gas chromatography/high-resolution mass spectrometry for routine monitoring of dioxin-like polychlorinated biphenyls in complex feed samples. Its precision, sensitivity, and cost-effectiveness make it well-suited for regulatory compliance and ensuring animal feed safety.