Evaluation of the effectiveness of om-85 bv combination therapy in chronic obstructive pulmonary disease at Bai Chay Hospital, 2024 – 2025
Tóm tắt
Background: Chronic obstructive pulmonary disease (COPD) is a major global health burden. Frequent exacerbations worsen lung function, quality of life, and healthcare costs. OM-85 BV (Broncho-Vaxom) is an oral immunomodulator derived from bacterial lysates, investigated for reducing respiratory infections and COPD exacerbations. Objective: To evaluate the clinical effectiveness of OM-85 BV in COPD patients at Bai Chay Hospital. Methods: A descriptive case-series study combining retrospective and prospective data was conducted in 119 outpatients with COPD (GOLD stage B or higher, ≥40 years old) between 2024 and 2025. Patients received standard COPD therapy plus OM-85 BV. Clinical data, exacerbations, antibiotic and corticosteroid use, and lung function (FEV1) were analyzed using SPSS 22.0. Results: OM-85 BV significantly reduced exacerbations, antibiotic and corticosteroid use, and improved lung function. Conclusion: OM-85 BV represents a promising adjunctive therapy for COPD management in Vietnam.
Keywords: COPD, OM-85 BV, Broncho-Vaxom, exacerbation, lung function
Background: Chronic obstructive pulmonary disease (COPD) is a major global health burden. Frequent exacerbations worsen lung function, quality of life, and healthcare costs. OM-85 BV (Broncho-Vaxom) is an oral immunomodulator derived from bacterial lysates, investigated for reducing respiratory infections and COPD exacerbations. Objective: To evaluate the clinical effectiveness of OM-85 BV in COPD patients at Bai Chay Hospital. Methods: A descriptive case-series study combining retrospective and prospective data was conducted in 119 outpatients with COPD (GOLD stage B or higher, ≥40 years old) between 2024 and 2025. Patients received standard COPD therapy plus OM-85 BV. Clinical data, exacerbations, antibiotic and corticosteroid use, and lung function (FEV1) were analyzed using SPSS 22.0. Results: OM-85 BV significantly reduced exacerbations, antibiotic and corticosteroid use, and improved lung function. Conclusion: OM-85 BV represents a promising adjunctive therapy for COPD management in Vietnam.
