Establish biochemistry reference intervals for Laboratory Center, Hanoi University of Public Health

Abstract

Objective: Establish biochemistry reference intervals suitable for the Laboratory center of Hanoi University of Public Health.

Methods: The study was carried out based on guidance of CLSI EP28-A3 using indirect sampling method. 8345 normal sample from January 2018 to April 2021 in Laboratory center of Hanoi University of Public Health is used.

Results: The results showed that the biochemistry reference intervals was established as below: GLU (3.94-6.38 mmol/L), men (3.94-6.48 mmol/L), women (3.95-6.26mmol/L); CHOL (3.46-6.06 mmol/L), male (3.55-6.10 mmol/L), female (3.44-6.02 mmol/L); TRI (0.46-2.20 mmol/L), male (0.56- 2.24 mmol/L), female (0.44-2.11 mmol/L); URE (2.62-7.10 mmol/L), men (2.93-7.32mmol/L), women (2.48-6.72mmol/L); CRE (53.62-107.09 µmol/L), men (68.58-111.14 µmol/L ), women (50.35-86.54 mol/L); AST (13.46-32.27 U/L, men (14.05-32.83U/L), female (13.03-30.99 U/L); ALT (7.21-34.14 U/L), men (7,91-35,06 U/L), female (13,03-30,99 U/L).

Conclusions: The reference intervals determined in our research have the signifcant differences to the reference intervals currently used in our laboratory.