Overview of foreign publications on new oral anti-coagulants (noac )also called direct oral anti-coagulants (doac )

Abstract

Novel oral anticoagulant (NOAC) is a new generation of anticoagulants. NOACs
partially disrupt the complex mechanism involved in the formation of blood clots. This
prolongs blood clot formation time and reduces the risk of (Atrial fibrillation(AF)-related
strokes. These are all drugs for oral use, with relatively high bioavailability, convenience,
effectiveness, and safety not inferior to older options such as vitamin K antagonists.
Comparison of pharmacokinetics and pharmacodynamics plays an important role in the
effective use of drugs and the reduction of adverse events. In this article, the
pharmacokinetics - pharmacodynamics of new oral anticoagulants and their application in
drug counseling for patients will be analyzed and discussed.