Developing formulas for calculating the dose of Levothyroxine in hypothyroidism patients treated at Hai Phong International Hospital in 2022

Tóm tắt

Thyroid hormone replacement therapy has been used for more than a century to treat hypothyroidism [1]. As levothyroxine is usually administered over a patient’s lifetime, physiological changes throughout life will affect the dose of levothyroxine required to maintain euthyroidism. This study conducted retrospectively on patients treated for hypothyroidism in the hospital Hai Phong International Hospital in 2022, aims to identify several factors that may affect a patient's daily dose of levothyroxine, including factors such as age, weight, comorbidities, along with several blood biochemical indicators including thyroid hormones and indicators of liver function and damage. From the 690 record samples collected and correlation results, we have come up with a regression equation calculating the dose of Levothyroxine for patients.