ĐÁNH GIÁ KHẢ NĂNG PHÂN TÍCH PHENOXYETHANOL TRONG VACCINE BẰNG PHƯƠNG PHÁP ĐIỆN HOÁ

Tóm tắt

Phenoxyethanol (2- Phenoxyethanol, 2-PE) is widely used as a preservative in the vaccines, cosmetics, and
pharmaceuticals. Currently, the content of 2-PE in products was analyzed by HPLC based on the strong absorption
of light at 270 nm wavelength of 2-PE, however, this analysis required highly skilled operators, was time-consuming,
and the cost of purchasing equipment was also high. Therefore, in this work, we proposed an investigation of the
electrochemical oxidation of phenoxyethanol (2-PE) on some types of electrodes, in some types of electrolyte
solutions for electrochemical determination of 2-PE. Inwhich, the selectivity, sensitivity, linearity detection range
were considered. Finally, measurements were conducted on real samples to evaluate the ability to analyze 2-PE by
electrochemical method. The successful study of the oxidation ability of 2-PE by electrochemical sensor could open a
new solution for rapid analysis of 2-PE with many advantages: low cost, easy-to-operate process and more time
saving than traditional methods.