ASSESSMENT OF ULTRASONIC EXTRACTION APPLIED IN DERTERMINATION OF PHARMACEUTICAL PRODUCTS AND PERSONAL CARE PRODUCTS (PPCPS) IN RIVER SEDIMENTS

Abstract

The study evaluated the ultrasonic extraction technique used in PPCP analysis in sediment samples by
comparing the results obtained by application of the ultrasonic extraction technique with those of ASE
extraction technique. It was found that no difference in recovery or repeatability in results of analysis
of sediment samples between applying ultrasonic extraction and ASE extraction. The analytical method
based on ultrasonic extraction has a recovery of 70 - 106% and a repeatability of ˂ 20%. PPCPs
analysis results in Cau river sediment samples show that PPCPs in Cau river sediment varied in the
range 113.0-215.2µg/kg with the tendency of increasing concentration along the river from up-stream
to downstream. CAF, SMZ, LIN and TRM are PPCPs had detection rate of 100% in sediment collected
in Cau River. CAF is the most dominant PPCP (10,22-139,4µg/kg) and SMZ is the antibiotic with the
highest concentration of the studied antibiotics (24.8-66.7µg/kg).