TỔNG HỢP HẠT NANO MnO BỌC POLY(VINYLPYRROLIDONE) VÀ ĐÁNH GIÁ ĐỘ TĂNG TƯƠNG PHẢN ẢNH TRONG CHỤP CỘNG HƯỞNG TỪ CHẨN ĐOÁN

Tóm tắt

In this work, poly(vinylpyrrolidone) coated MnO nanoparticles (MnO@PVP NPs) were prepared by the
polyol method using triethylene glycol (TEG) and poly(vinylpyrrolidone) (PVP) as solvents and surfactants.
The materials' structure, morphology and characteristic properties were analyzed using XRD, TEM, FTIR
and DLS measurements. MnO nanoparticles synthesized under optimized conditions have a spherical shape
with an average size of 10.87 ± 1.19 nm, demonstrating good image contrast signal enhancement in
magnetic resonance imaging (MRI) diagnostic techniques. Research results show that nano MnO@PVP NPs
have a high value of longitudinal relaxivities r1 (5.28 mM-1
s
-1
), reducing longitudinal relaxation times T1
and thus increasing MRI signal intensity. The research results show that PVP-coated MnO nanoparticles
can be used as T1 positive contrast agents for diagnostic imaging applications shortly.