SYNTHESIS OF HYBRID COMPOUND OF 24-NOR-LUPANE TRITERPENE AND 11-AMINO-UNDECANOIC ACID VIA C-28 AMIDE LINKAGE

Abstract

Starting from 24-nor-3-oxo-20(29)-lupen-28-oic acid (1), a new derivatives (2) have been synthesized. The synthetic approach C-28 amide conjugates of 1 with 11-amino-undecanoic acid was described in this report.  The new hybrid containing two biologically active moieties via a amide linkage. The chemical structure of 2 was elucidated mass (MS), nuclear magnetic resonance (NMR) spectroscopy.