Development and validation of quantitative procedure of clotrimazole and eugenol in gel product using high-performance liquid chromatography

  • Mong To Tam Tran, Thi Thanh Vy Dinh, Hoai Hieu Vo, Thi Hoang Yen Pham, Thi Loan Le
  • Dinh Nga Nguyen
Từ khóa: antibacterial activity, antifungal activity, clotrimazole, high-performance liquid chromatography, Ocimum gratissimum essential oil

Tóm tắt

Vulvovaginitis is a prevalent gynaecological ailment worldwide, often attributed to bacteria, Candida fungi, or Trichomonas. The synergistic action of antifungal agents and essential oils can enhance the efficacy against pathogenic microorganisms. In this study, a simultaneous quantitative method for determining clotrimazole and eugenol in a laboratory-compounded gel product was developed using high-performance liquid chromatography
with a photodiode array detector (HPLC-PDA)...

Tác giả

Mong To Tam Tran, Thi Thanh Vy Dinh, Hoai Hieu Vo, Thi Hoang Yen Pham, Thi Loan Le

Yersin University, 27 Ton That Tung Street, Ward 8, Da Lat City, Lam Dong Province, Vietnam

Dinh Nga Nguyen

University of Medicine and Pharmacy at Ho Chi Minh City, 217 Hong Bang Street, Ward 11, District 5, Ho Chi Minh City, Vietnam

điểm /   đánh giá
Phát hành ngày
2024-06-15
In ra
Số. 2C (2024): JUNE 2024 . VOLUME 66 NUMBER 2
Chuyên mục
PHYSICAL SCIENCES