BUILDING ALCALOID EXTRACT PROCESSING FROM THE ROOTS OF STEMONA IN THAI NGUYEN

Abstract

Stemona is a precious medicine from nature that has been used for thousands of years in health and healing support. Stemona contains many precious compounds, including the alcaloid compounds that fight against cough, skin diseases and liver cancer. The effects of extraction temperature, extraction time and material/solvent ratio on extraction process of alcaloid content from root of stemona in Thai Nguyen were studied, extraction solvent is chloroform, ethanol and methanol. The results showed that the concentration of alcaloid in stemona was 1.18% compared to the raw material, data analysis showed that the amount and concentration of alcaloid were affected by two factors including temperature and extraction times. The extraction time (4 hours), the extraction temperature (60^oC), ethanol 80^o, the material/solvent ratio (1/8) for the 0.172 grs and the total alkaloid content is 57.17%. The total alkaloid extraction was performed by ultrasonic immersion, totaling alcaloid by tuberostemonin by acid-base titration.