Characteristics of urinary tract infection bacterial pathogens and antimicrobial resistance profiles at Hai Phong Medical University Hospital in 2024

Abstract

Objectives: 1) identify the prevalence of bacterial pathogens causing UTIs and their antibiotic resistance profiles. Subjects and methods: A cross-sectional descriptive study was conducted on 390 inpatients clinically diagnosed with UTI, with positive urine cultures and underwent antibiotic susceptibility testing at Hai Phong Medical University  Hospital in 2024. Results: Gram-negative bacteria accounted for a high proportion (79%), primarily Escherichia coli (62.3%) and Proteus spp. (6.9%). The most commonly isolated Gram-positive bacterium was Staphylococcus spp. (10.8%). E. coli exhibited resistance to various antibiotics, with resistance rates to cephalosporins and quinolones ranging from 44% to 77.3%, and 12.7% resistance to carbapenems. ESBL-producing E. coli strains showed higher resistance levels than non-ESBL-producing strains. Staphylococcus spp. was resistant to cefoxitin in 60% of cases but showed no resistance to nitrofurantoin. Conclusion: The isolated bacteria displayed varying degrees of resistance to many commonly used antibiotics, with the notable emergence of carbapenem-resistant strains.