Association between subclinical characteristics and severity of Dengue fever patients in Hai Phong in 2023

Abstract

Dengue fever is an infectious disease that causes liver damage and hemorrhage, and early detection of factors related to severe prognosis of dengue fever is valuable in the diagnosis and treatment of the disease. Objective: to describe subclinical characteristics and determine the association with the severity of dengue fever patients in Hai Phong in 2023. Subjects and methods: collected information from the medical records of 278 patients diagnosed and treated for dengue fever at Viet Tiep Hospital from September 2023 to December 2023. Results: AST, ALT, red blood cell count, hematocrit, white blood cell count, and platelet count significantly differed between disease severity (p < 0.01). The prognostic value for dengue fever severity of AST at the cut-off point of 101.45 U/L (sensitivity 80%; specificity 89.4%) and ALT at the cut-off point of 68.65 U/L (sensitivity 80%; specificity 83.4%) were highly reliable. Conclusion: AST and ALT levels are simple but meaningful tools for predicting the severity of dengue fever. Doctors can consider using these indicators in combination with clinical symptoms to provide treatment and reduce the risk of complications and mortality for patients.