Clinical, paraclinical features and treatment results of patients with Kawasaki disease

Abstract

Objectives. The study aimed to describe the clinical and paraclinical features and evaluate the treatment outcomes of patients with Kawasaki disease at Haiphong Children’s Hospital from 2019 to 2023. Subjects and Methods. A case series report was conducted on 57 patients with Kawasaki disease. Results and Conclusions. Kawasaki disease was most common in children aged 6–24 months (80.7%) and affected more males than females (64.9% vs. 35.1%). Fever was present in 93.0% of cases, bilateral conjunctivitis in 67.7%, red or blistered lips in 82.5%, and red tongue or bumps in 78.9%. Erythema multiform was observed in 73.7%, cervical lymphadenitis in 71.9%, and edematous changes in the extremities in 50% of patients. 38.6% of patients were diagnosed within the first 5 days. The typical form accounted for 86.5% of cases, while the atypical form accounted for 13.5%. White blood cell count, platelets, and CRP were elevated in most patients; notably, 82.5% had a white blood cell count greater than 10 G/L. Coronary artery lesions were present in 17.5% of cases, with 15.8% involving the left coronary artery and 7.0% involving both coronary arteries. Treatment outcomes showed that 61.4% of cases were stable or cured, 22.8% were transferred to higher-level hospitals, and 15.8% showed no improvement. 75.7% of cases had no complications, while 24.3% developed coronary artery dilatation.