Bacterial pathogens identified in foot damages of diabetic patients during the period 2019-2021 in Viet-Czech Friendship hospital

Abstract

Objectives: Study was done to evaluate the bacteriological characteristics of foot injury in diabetic patients at Viet Tiep Hospital in Hai Phong in the year 2019 - 2021 and to comment on the antibiotic susceptibility of the above pathogenic bacteria. Subjects and Methods: Descriptive study on 81 diabetic patients with foot injury. Results: Male > female ratio, mean age 67,2±11,5 years old. Bacterial growth rate was 71,6%: 42,0% Staphylococcus aureus, 13,0% Escherichia coli, 10,1% Klebsiella pneumoniae, 2,9% Pseudomonas aeruginosa. 62,3% Gram-positive bacteria and 37,7% Gram-negative bacteria. Antibiotic sensitivity: Staphylococcus aureus 100% resistant to Penicillin, 100% sensitive to Vancomycin, 83,3% sensitive to Doxycycline. Gram-positive bacteria Staphylococcus agalactiae are still 100% sensitive to Vancomycin, 80% Penicillin G, 80% Levofloxacin. Gram-negative bacteria (Escherichia coli, Klebsiella pneumoniae, Proteus mirabilis, Enterobacter cloacae) sensitive to 90,9% Piperacillin/Tazobactam, 96% of antibiotics in the group Carbapenem, amikacin and resistant to Ciprofloxacin 44,4%, Gentamicin 42,8%. Conclusion: Antibiotics are effective against bacteria causing diabetic foot infections at Viet Tiep Friendship Hospital in 2019-2021, of which Vancomycin, Levofloxacin, Piperacillin/Tazobactam, Carbapenem, Amikacin still has a high sensitivity rate to bacteria. Penicillin is only active against common Gram-positive bacteria. Ciprofloxacin has an increasing prevalence of resistant Gram-negative bacteria. More extensive research is needed to assist clinicians in empiric antibiotic selection before antibiograms are available.