Bacopa monnieri extract ameliorates core autistic behavioural deficits of sodium valproate-induced autism spectrum disorder in mice, and its mechanism of action related to PTEN protein

  • Thi Nguyet Hang Pham*, Nguyen Hong Tran, Thi Xoan Le
  • Anh Tung Pham, Thi Lap Nguyen
  • Thi Hien Nguyen
Keywords: anxiety, ASD, Bacopa monnieri, self-repetitive behaviour, social interaction, sodium valproate.

Abstract

Our previous study demonstrated the effect of Bacopa monnieri extract (BME) on behavioural deficits in sodium valproate (VPA)-induced autism spectrum disorder in mice. The present study aims to further investigate the effect of BME on neurobehaviors of autism spectrum disorder (ASD) in mice and the biochemical mechanism(s) involved...

Tác giả

Thi Nguyet Hang Pham*, Nguyen Hong Tran, Thi Xoan Le

Department of Pharmacology and Biochemistry, National Institute of Medicinal Materials

Anh Tung Pham, Thi Lap Nguyen

Hanoi University of Pharmacy

Thi Hien Nguyen

Ha Dong Medical College

điểm /   đánh giá
Published
2022-05-20