Identification of mutation in G6PD gene in Nung ethnic patients with glucose-6-phosphate dehydrogenase deficiency

Abstract

Glucose-6-phosphate dehydrogenase (G6PD) is the key enzyme that initiates the pentose phosphate cycle in glucose metabolism. Physiologically, this pathway is the main source of nicotinamide adenine dinucleotide phosphate (NADPH) for red blood cells...