Screening for carriers of the SRD5A2 gene mutation 5-alpha-reductase 2 deficiency in Vietnamese pregnant women

  • Thi Trang Nguyen, Doan Trang Nguyen, Hoang Dan Le, Thi Ngoc Anh Le
  • Quang Anh Pham, Thanh Sang Nguyen
  • Toan Anh Ngo, Thanh Tuan Nguyen*
  • Thai Thanh Hoang, Huu Hao Ha
  • Duc Nhu Nguyen
  • Thi Huyen Trang Do
Keywords: SRD5A2 gene mutation, Vietnamese pregnant women, 5-alpha-reductase 2 deficiency.

Abstract

Objective: To describe the percentage of people who carry the SRD5A2 gene mutation causing 5-alpha-reductase 2 deficiency and the characteristics of their mutated variants in Vietnamese pregnant women. Subjects and methods: A cross-sectional descriptive study was conducted on 8,464 pregnant women who visited and agreed to perform a screening test for gene carriers related to recessive genetic conditions at the Institute of DNA Technology and Genetic Analysis...

Tác giả

Thi Trang Nguyen, Doan Trang Nguyen, Hoang Dan Le, Thi Ngoc Anh Le

Hanoi Medical University, 1 Ton That Tung Street, Trung Tu Ward, Dong Da District, Hanoi, Vietnam

Quang Anh Pham, Thanh Sang Nguyen

Thai Binh University of Medicine and Pharmacy, 373 Ly Bon Street, De Tham Ward, Thai Binh City, Thai Binh Province, Vietnam

Toan Anh Ngo, Thanh Tuan Nguyen*

National Hospital of Obstetrics and Gynecology, 43 Trang Thi Street, Hang Bong Ward, Hoan Kiem District, Hanoi, Vietnam

Thai Thanh Hoang, Huu Hao Ha

Institute of DNA Technology and Genetic Analysis, 112 Trung Kinh Street, Yen Hoa Ward, Cau Giay District, Hanoi, Vietnam

Duc Nhu Nguyen

National Institute of Forensic Medicine, 41 Nguyen Dinh Chieu Street, Le Dai Hanh Ward, Hai Ba Trung District, Hanoi, Vietnam

Thi Huyen Trang Do

Hanoi Medical University, Thanh Hoa Branch, 722 Quang Trung Street, Dong Ve Ward, Thanh Hoa City, Thanh Hoa Province, Vietnam

điểm /   đánh giá
Published
2024-07-25
Issue
Vol. 66 No. 7B (2024): TẬP 66, SỐ 7, THÁNG 7 NĂM 2024
Section
Bài viết