Screening the culture medium and optimal fermentation conditions for the production of transglutaminase by the Streptomyces sp. strain TG1G1

Abstract

Microbial transglutaminase (MTGase) catalyses the creation of isopeptide bonds between the γ-carboxamide group of the glutamine residues as acyl donors and the ε-amine group of different compounds as a receptor that modifies protein structure. This research objective was to improve the transglutaminase activity produced by a strain of Streptomyces sp. TG1G1 by choosing an appropriate medium and optimising fermentation conditions...