The value of diffusion-weighted and T2W-weighted magnetic resonance imaging in evaluate extracapsular extension in prostate cancer

Tóm tắt

   Objective: The objective of our study was to evaluate the value of diffusion and T2-Weighted on magnetic resonance imaging for predicting extracapsular extension (ECE) in patients with prostate cancer.
   Materials and methods: We evaluated ECE with T2-weighted imaging based on the Prostate Imaging Reporting and Data System (PI-RADS). The results we confirm by surgical pathology. We compared MRI characteristics between patients with ECE Prostate carcinoma (PA), and those without ECE Prostate carcinoma (pica) using independent sample t-tests, Chi- square tests, as appropriate. Analyzing ROC curve to find the value of T2W score in ECE and those without ECE to have a high specificity for ECE of prostate cancer.
   Results: Age mean in ECE PCa was 67.03 ± 7.26. ECE PCa had 54.55%. Patients with ECE PCa have mean T2 scores was 3.64 ± 1.29, mean ADC values was 494.58 ± 95.06x10^-6 mm²/s, mean ADC ratio was 39.45 ± 9,05%. On ROC curve, using the discrimination threshold of T2W score > 2, AUC was 0.938, sensitivity 83.3%, specificity was 96.7%, positive predictive value was 96.8%, negative predictive value was 82.9%, mean ADC value was 477.41 ± 86.48x10^-6 mm²/s, mean ADC ratio was 38.37 ± 8.68%.
   Conclusion: MRI is benefit from evaluate extracapsular extension (ECE) in patients with prostate cancer. T2W score > 2, AUC is 0.938, sensitivity 83.3%, specificity is 96.7%, positive predictive value is 96.8%, negative predictive value is 82.9%, mean ADC value is 477.41 ± 86.48 x10^-6 mm²/s, mean ADC ratio is 38.37 ± 8.68%.

DOI: 10.59715/pntjmp.5.2.8