Some compounds from the fraction with the best antioxidant activity of the species Murdannia bracteata
Abstract
Murdannia bracteata is a wild plant in Can Tho City in particular and in Vietnam in general. This is a rich source of raw materials, easy to find, but up to now, domestic and world research on this plant is limited. Therefore, the project was carried out to study the chemical composition according to antioxidant orientation of total and fractional extracts (diethyl ether, ethyl acetate, n-butanol, water) from M. bracteata using DPPH test (1,1-diphenyl-2-picrylhydrazyl) with vitamin C as reference. The results of the project have determined that the ethyl acetate fraction of M. bracteata has the strongest antioxidant activity, with IC50 = 881.66 µg/mL. From the ethyl acetate fraction of M. bracteata, after repeated chromatography and purification, we have isolated and identified the structures of 4 compounds: apigenin (compound 1), kaempferol-3-O-rhamnoside (compound 2), pimaric acid (compound 3) and quercetin (compound 4). Compounds (2) and (3) were found for the first time in the species M. bracteata grown in Can Tho City compared to previous studies. The results of this study provide a database for further research on biological effects in M. bracteata.
