A review of 18F – FDG PET/CT imaging characteristic in B cell non hodgkin’s lymphoma at Hanoi Oncology Hospital

Abstract

Objective: This study aimed to review 18F-FDG PET/CT imaging characteristics of B cell Non-Hodgkin’s lymphoma at Hanoi Oncology Hospital.

Materials and Methods: A retrospective descriptive study was conducted on 86 newly diagnosed B cell Non Hodgkin’s lymphoma by histopathology and immunohistochemistry at Hanoi Oncology Hospital from January 2018 to December 2022. Those patients undergone 18F-FDG PET/CT scans for pre-treatment staging.

Results: Among 86 B cell NHL patients, 38 female and 48 male with mean age was 58.1 ± 16.2. There were 72 patients with aggressive NHL, in which DLBCL accounted for 45.3%. According to PET/CT imaging, the highest frequency lymph nodes were cervical and abdominal lymph nodes with 65.1% and 53.5%, correspondingly. The other lymph nodes were mediastinal (34.9%), axillary (30.2%) and inguinal (22.1%). PET/CT showed 23 extranodal sites/organs, most commonly were tonsil (16.3%), spleen (9.3%), bone marrow (9.3%), stomach (8.1%), nasopharynx (7.0%). The median SUVmax of aggressive NHL was 11.3, indolent NHL was 5.4, p < 0.01. Analysis of the correlation between size and SUVmax showed rs = 0.547, p< 0.01.

Conclusions: PET/CT helps to detect lesions of B cell NHL at many sites. The SUVmax value of aggressive group higher than indolent group. This study show there was a positive correlation between size and SUVmax.