Diagnostic determination neural axon injury linked between two hemispheres post-trauma brain injury by diffusion tensor imaging: A case report

Abstract

Traumatic brain injury (TBI) is a form of acquired brain injury resulting from an external mechanical force to the head make up the alternation of brain function. However, it is difficult to diagnose the injury to the neural tract and the connection between us through traditional imaging techniques. A 54y woman came to our clinic because of insufficient coordination of her body. Her personal history: Severe trauma brain injury with coma in 10 days treated by medical treatment 10 years ago. Some bad conditions after TBI include impairment of memory, insufficiency of coordination of her body, a post-concussion syndrome was suggested. Clinical examination: GCS: 15, strength testing: 5/5 for both sides but our patient can’t walk. She was examined at many medical centers but no evidence conforming her symptom. Our patient scanned by MRI ((Magnetic resonance imaging) Siemens 3.0 Tesla Spectra system. MRI morphometry used for her detected a significant decline of corpus callosum. MRI - DTI (Diffusion Tensor Imaging) revealed a decreased FA in the white matter of the right temporal and corpus callosum. Fractional anisotropy is a scalar value between zero and one that describes the degree of anisotropy of a diffusion process. A decrease in the value of FA in corpus callosum is indicative of the loss of connection between both hemispheres. MRI tractography used to describe the amount of neural tracts in corpus callosum. So, MRI-DTI and MRI Tractography served as a powerful diagnostic tool, providing imaging results that offered an explanation for our patient’s clinical picture