Primary hepatic angiosarcoma: a case report

Abstract

We report a case who was diagnosed with primary hepatic angiosarcoma (PHA). A 62-year-old man presented with right upper quadrant abdominal pain, weight loss, and hepatomegaly. He did not have a history of carcinogen exposure or any relevant medical history. On laboratory evaluation, the patient had an elevation of white blood cell count, AST, ALT and anemia. The levels of serum carcinoembryonic antigen, carbohydrate antigen (CA)-19-9, α-fetoprotein, and PIVKA-II were normal. Abdominal ultrasound, computed tomography, and magnetic resonance imaging revealed a large lesion in the right lobe of the liver and a small lesion in the left lobe of the liver which are non-specific images. The patient underwent liver biopsy and histopathological examination confirmed PHA. PHA is a rare disease that usually occurs in the sixth decade of life, and males are more frequently affected than females. In most cases, the cause is unknown. Clinical symptoms and laboratory evaluation of PHA are nonspecific. There is no pattern recognition in diagnostic imaging. Liver biopsy and histopathology confirmed the presence of PHA.