Appearance of focal nodular hyperplasia after chemotherapy in patient during follow up of gastric cancer

Abstract

Chemotherapy could induce multiple liver parenchymal and vascular disorder presenting as diffuse or focal lesion. Focal nodular hyperplasia (FNH) – like nodules is benign lesions that should be distinguish to hepatic metastasis because they associate with further interventions and treatments. The main machanism of the apperance of FNH is Oxaliplatin-induced portal venous injuries called hepatic sinusoid obstruction syndrome (HSOS). Here, we present a case of the development of FNH – like nodule during follow up of gastric carcinoma after adjuvant treatment with XELOC chemotherapy (Oxaliplatin-based chemotherapy)