Evaluate the clinical effectiveness of intradiscal Ozone injection combining periradicular injection of Ozone and steroid under CT guidance for the treatment of lumbar disc herniation

Abstract

Background: back pain and sciatica caused by disc herniation has a burden upon social activity. The newly minimally invasive technique, percutaneous Ozone (O2-O3) intradisal injection procedure has demonstrated safe and effective in long terms.

Purpose: Evaluate the clinical effectiveness of intradiscal Ozone injection combining periradicular injection of Ozone and steroid under CT guidance for the treatment of lumbar disc herniation.

Material and method: Prospective study, 100 patients symtomatic (lumbar pain, sciatica) with mild/moderate lunbar disc bulging or herniation on MRI. The patients were treated with intradiscal Ozone injection combining periradicular injection of Ozone and steroid under CT guidance. Clinical outcomes and MRI images were reviewed to evaluate at 3 months and 6 months.

Results: The VAS score and the Oswestry Disability Index (ODI) before and after treatment 3months, 6 months were significant reduction. The mean improvement was 4.7 for VAS and 14 for ODI. All the procedures were technically successful. There were no adverse events associated with the treatment. Conclusion: Intradiscal injection Ozone treatment of herniated disc is an minimally invasive, easy, safe and effective procedure with low complications and side effects.