Some clinical features, characteristics of 18FDG uptake of tumors and nodes on PET/CT in patients NSCLC with indications for radical surgery at Hanoi Oncology Hospital

Abstract

Purpose: To review some clinical features, characteristics of 18FDG uptake of tumors and lymph nodes on PET/CT in NSCLC patients with indications for radical surgery at Hanoi Oncology Hospital.

Subjects and methods: 82 patients with primary NSCLC were taken with 18FDG PET/CT before surgery.

Results: Right lung tumor 64.6%, left lung tumor 35.4%. The average size of the tumor was 2.6 ± 1.0 cm, the patient with lymph node (+) on PET/ CT had an average lung tumor size of 3.3 ± 0.9cm; larger than patients with N0 lymph nodes (p < 0.05). The mean SUVmax of lung tumors was 6.0 ± 4.5 and increased with tumor size (positive correlation, r=0.58). U ≤2cm, SUVmax = 4.1 ± 2.1. U >2-3cm, SUVmax = 5.3 ± 3.6 and U >3 -5cm, SUVmax = 8.3 ± 4.9. SUVmax increases with clinical disease stage and is higher in patients with positive lymph nodes on PET/CT.

Conclusion: 18FDG PET/CT plays an important role in the diagnosis of NSCLC. SUVmax is a quantitative parameter related to tumor size, lymph node status and clinical disease stage